Cachexia is a multifaceted condition characterized by persistent muscle loss that cannot be entirely reversed with standard nutritional support, resulting in diminished functionality. It may be masked by excess weight, obesity, edema, or tumor mass. Anorexia is defined as a reduced appetite, frequently observed in cancer patients, though its precise prevalence remains unclear. MMJ Express Canada offers valuable information on this topic.
When cachexia primarily stems from decreased intake, it is termed cancer-related cachexia and anorexia syndrome (CACS). This condition encompasses muscle wasting, lipolysis, and reduced food intake, differentiating it from simple cachexia. Research suggests that cannabis from MMJ Express Canada could potentially enhance appetite and mitigate nausea in cancer patients.
Table of Contents
Key Takeaways:
- THC capsules might assist cancer patients in consuming more food and feeling less nauseated, thus improving their quality of life.
- Studies show that cannabis influences brain cells responsible for hunger, which may aid in addressing appetite concerns in cancer patients and others.
- THC capsules are precise, convenient, discreet, and long-lasting, making them suitable for medical cannabis users who prefer not to smoke.
Cancer Cachexia and Anorexia Syndrome
Cachexia is a condition characterized by significant weight loss due to the depletion of muscle and fat, commonly seen in patients with advanced illnesses such as heart failure, HIV/AIDS, COPD, kidney failure, and particularly cancer. cannabis can play a role in managing symptoms effectively.
This condition is often accompanied by anorexia, leading to at least a 5% reduction in body weight. Together, they constitute cancer anorexia-cachexia syndrome (CACS). Hospitalized cancer patients frequently exhibit inadequate dietary intake, with nearly half being malnourished or at risk. Cachexia not only affects patients’ quality of life but also hinders treatment and can hasten the end of life. Its occurrence spikes as death approaches, with cachexia cited as a primary cause of death in over 20% of cases.
Despite being widespread, CACS often goes unnoticed and untreated in clinical environments due to ambiguous definitions, diagnostic criteria, classification systems, and approved therapies. Clinicians evaluate a patient’s nutritional status through various metrics like body weight and skin fold thickness, although body weight is often the primary measurement, typically using inappropriate reference weights.
Treatment
Improving nutrition is the most straightforward approach to addressing anorexia; however, evidence supporting its efficacy remains limited. Nutritional care for cancer patients includes:
- Dietary Counseling
- Oral Supplements
- Enteral and Parenteral Nutrition
Nevertheless, success varies based on the type and stage of cancer involved, and cannabis can help enhance these efforts.
Pharmacological Approaches
Currently, no verified medications treat Cancer Anorexia-Cachexia Syndrome (CACS), but several drugs are utilized off-label or are undergoing clinical trials. These medications fall into four categories based on their mechanisms:
- Appetite Stimulants
- Cytokine Modulators
- Anabolic Agents
- Combination Therapies
Additionally, megestrol acetate, a progestin, is separately utilized due to its unclear mechanism of action.
Cannabis in Medicine
The cannabinoid could enhance the lives of cancer patients and pave the way for future treatments. This provides hope for cachexia patients, who often experience appetite loss and malnourishment. It offers relief without intoxicating effects, positioning it as a potential solution for these patients.
Various cannabis formulations are available, including inhaled THC for rapid onset and short-lived effects, and orally ingested THC for slower absorption and prolonged effects. Sublingual administration provides rapid onset lasting 2 to 4 hours.
Clinical Trial
A study conducted by researchers from Israel and the United States examined how cannabis pills impact CACS in advanced cancer patients. This research considerably influences the treatment of appetite disorders, including those faced by cancer patients, individuals with anorexia, and potentially obesity.
Methods
The study utilized cannabis capsules containing two types of oil-based compounds. Participants were treated with 10 mg doses twice daily for six months, comprising 9.5 mg of tetrahydrocannabinol (THC) and 0.5 mg of cannabidiol (CBD).
If participants experienced side effects, the dose was reduced to 5 mg twice daily (4.75 mg THC and 0.25 mg CBD). During each doctor’s visit, participants were weighed, aiming for at least a 10% increase in weight from their initial measurement.
Results
Out of 24 patients who consented to participate, 17 initiated treatment with cannabis capsules. However, only 11 continued for more than two weeks. By the study’s conclusion, 3 out of 6 patients who completed the treatment achieved the primary goal of gaining at least 10% more weight. The weight of the remaining three patients remained stable.
After treatment, tumor necrosis factor-α (TNF-α), an inflammation marker, decreased. Patients reported improved appetite, mood, and reduced pain and fatigue.
Despite various challenges, this preliminary study demonstrated a 10% or more weight gain in 3 out of 17 patients (17.6%) taking daily doses of 5 mg without significant side effects. These results advocate for a larger, more controlled study on cannabis capsules for patients with CACS.
Cannabis Capsules
For those who prefer edibles, cannabis flower, or classic pre-rolls, discovering new consumption methods is always intriguing. THC capsules are among the latest innovations in the cannabis market. These capsules are cannabis pills containing a precise dose of THC, derived from concentrated cannabis extract and a neutral oil. They resemble cannabis tinctures but are in capsule form, often referred to as cannabis oil capsules or THC pills.
Key Components
- Cannabis Extract: This concentrated extract comes from the cannabis plant using a method chosen by the manufacturer for extraction. THC capsules are rich in THC, although some may solely contain CBD or varying CBD/THC ratios.
- Neutral Oil Suspension: THC is not water-soluble, so it is suspended in oil for effective absorption by the body. The most common oils include medium-chain triglycerides (MCT oils), which assist in digestion and absorption.
Benefits
Both medical marijuana patients and recreational users can experience advantages from cannabis capsules, including:
- Convenience: Taking a cannabis capsule is as straightforward as consuming any other oral supplement. Just swallow it with water, hassle-free.
- Precision Dosage: For medical users, exact control over cannabinoid intake is essential for achieving desired effects. With THC capsules, each dose is measured, eliminating uncertainty.
- Smoke-Free Option: Many individuals prefer to avoid smoking or vaping due to personal choices or health considerations. THC capsules provide a smoke-free alternative, suitable for those with respiratory concerns.
- Longer Effects: Capsules typically deliver longer-lasting effects compared to smoking or vaping, making them ideal for sustained symptom relief over several hours.
Cannabis Capsules vs. Other Forms of Medicinal Cannabis
| Aspect | Cannabis Capsules | Other Forms of Medicinal Cannabis |
| Dosing | Precise dosing with each capsule | Dosing may vary depending on the method of consumption (e.g., smoking, vaping, edibles) |
| Consumption | Oral ingestion | Smoking, vaping, edibles, tinctures |
| Effects | Longer-lasting, gradual onset | Immediate onset, shorter duration |
| Effects on Appetite Stimulation | Gradual stimulation | Immediate stimulation |
Place a Medical Cannabis Delivery Order Conveniently
As the demand for dependable cannabis delivery services rises, online dispensaries provide an efficient solution. From same-day cannabis delivery to quality cannabis products, these dispensaries offer a variety of options to meet diverse preferences and needs.
If you’re in search of cannabis flower, pre-rolls, edibles, or vape pens, you can easily explore MMJ Express Canada’s premium marijuana products sourced from top-quality marijuana plants. Shop for your favorite THC products from the comfort of your home.
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Frequently Asked Questions
What are the different types of capsules?
One additional benefit of cannabis pills/capsules is their versatility. Formulators can create various capsule types for consumers to choose from, ensuring options that align with personal preferences.
- 1:1 Capsules: These capsules provide an equal ratio of THC to CBD per dose, available in various concentrations like 5 mg, 20 mg, 50 mg, or 100 mg cannabinoids per capsule.
- 3:1 Capsules: These capsules offer a ratio of 3 parts CBD to 1 part THC per dose.
- THC Capsules: These capsules contain THC exclusively, with varying concentrations per capsule, derived from different Sativa or Indica strains to deliver specific effects.
- CBD Capsules: These contain only CBD, devoid of THC, thus not producing mind-altering effects. They cater to those seeking the benefits of CBD alone.
How do capsules interact with your body?
- The outer shell of the capsule disintegrates in your digestive tract after consumption.
- The contents of the capsule are absorbed into the bloodstream.
- THC (and other cannabinoids) are metabolized in the liver.
How long does it take for cannabis capsule effects to kick in?
Typically, THC capsules take about 90 minutes to start showing effects. The effects can last anywhere from 5 to 12 hours, gradually decreasing in intensity. Compared to inhaled cannabis, capsule effects generally last twice as long on average.
However, experiences may vary based on factors such as age, medications, individual cannabis tolerance, and cannabinoid composition. Some users also report differing effects based on specific cannabinoids present, likely due to the “entourage effect.”
How to mail order marijuana?
To mail order recreational cannabis, locate a trustworthy delivery service online that offers high-quality cannabis products. After selecting your products, opt for “order cannabis delivery,” and a delivery driver will safely bring your order. Ensure the service is reputable for a seamless purchasing experience.Related Articles:
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